Ncert – Class 12- Biology-Human Health and Disease

Welcome to your Ncert - Class 12- Biology-Human Health and Disease

Instruction

Total Questions : 20

Total Marks : 20 x 3 = 80 Marks

Each Correct Question carries : 4 Marks

Each incorrect Question Carries : -1 Marks

Each Unattempted Question carry : 0 Marks

Be careful On Negative Markings

Select the correct combination of statements regarding myasthenia gravis.

I. It is an autoimmune disorder.

II. It causes insufficient acetylcholine binding that effects muscular contraction.

III. Antibodies are developed against acetylcholine.

IV. Antibodies are developed against acetylcholine receptors.

V. It causes drooping of eyelids.

I, III, V, II

I, II, IV, V

I, III, IV, V

II, III, IV, V

None

Read the following statements regarding the HIV virus.

A. It is a type of retrovirus that has an envelope enclosing the diploid RNA genome.

B. It multiplies in helper T cells and produces progeny virus.

C. In the macrophages of the host, the RNA genome of the virus replicates to form viral DNA.

D. Reverse transcriptase becomes inactive in the host cell.

How many of the above statements are correct?

None

Identify the incorrect statement about the HIV virus.

HIV contains uracil, not thymine.

HIV infection begins with the entrance of the virus into the host when the gp 120 and gp 41 function to pull the virus across the plasma membrane.

HIV makes the host cell produce reverse transcriptase.

The viral nucleotides contain ribose.

None

Note the following features and choose the ones applicable to Wuchereia bancrofti.

A) Coelozoic parasite

B) Histozoic parasite

C) Monogenetic parasite

D) Digenetic parasite

E) Monomorphic acoelomate parasite

F) Dimorphic pseudocoelomate parasite

A, C, F

B, D, F

B, C, F

B, C, E

None

Cancer cells differ from non-cancerous cells, because

They have the ability to resist apoptosis

They can maintain the telomere length as they divide

Theya are virtually immortal

They have elevated levels of telomerase

None

Match the followingParasites and Migration Types

List I	List II
A. Entamoeba histolytica	I. Cytozoic parasite
B. Plasmodium	II. Coelozoic parasite
C. Wuchereria	III. Rhabditiform larva
D. Extra intestinal migration	IV. Monogenetic parasite
	V. Lymphadenitis

A- V, B- I, C- II, D- III

A- IV, B- V, C- I, D- III

A- IV, B- I, C- V, D- III

A- IV, B- II, C- V, D- I

None

The psychological disorder, which is characterised by sadness, helplessness, low self-esteem, decline in interest, energy, concentration and changes in sleep pattern and appetite is called

Mood disorder

Attention deficit disorder

Anxiety disorder

Obessive-compulsive disorder

None

Which of the following human parasites require mosquito to complete their life-cycle?

Leishmania donovani and Plasmodium ovale

Wuchereria bancrofti and Plasmodium ovale

Ascaris lumbricoides and Leishmania donovani

Ascaris lumbricoides and Wuchereria bancrofti

None

Which of the following statement is correct?

None of the above.

Vaccination is a technique to develop immunity in individuals by giving them antibiotics.

Tuberculosis, commonly called as T. B., is a viral disease common among poor people living in ill-ventilated congested societies in big cities.

The immune system is involved in protecting the body from disease.

None

10.

Choose the correct order of events in a persons response to a bacterial infection

Clonal formation → → Helper T cell activation → → B cell activation → → macrophage ingestion

Macrophage ingestion → → B cell activation → → T helper cell activation → → clonal formation

Helper T cell activation → → B cell activation → → macrophage ingestion → → clonal formation

Macrophage ingestion → → Helper T cell activation → → B cell activation → → clonal formation

None

11.

The suspension of killed microbes that mimics the disease causing microorganisms is known as

Antibiotics

Vector

Pathogen

Vaccines

None

12.

Select the correct combination of statements regarding the disease, myasthenia gravis.

(i) It is an autoimmune disorder.

(ii) It causes insufficient acetylcholine binding that affects muscular contraction.

(iii) Antibodies are developed against acetylcholine.

(iv) Antibodies are developed against acetylcholine receptors.

(v) Antibodies are developed against acetylcholine esterase.

(vi) It causes drooping of eyelids.

(i), (ii), (iv), (vi)

(ii), (iii), (iv), (v)

(i), (iii), (v), (vi)

(i), (iii), (iv), (vi)

None

13.

Which of the following are the reasons for rheumatoid arthritis? Choose the correct option.

I. Lymphocytes become more active

II. Body attacks self-cells

III. More antibodies are produced in the body

IV. The ability to differentiate pathogens or foreign molecules from self-cells is lost

III & IV

I & II

II & IV

I & III

None

14.

In the cycle of Ascaris lumbricoides, rhabditiform larva undergoes 2nd and 3rd moultings in

Alveoli of lungs

Small intestine

Liver

Heart

None

15.

Select the wrong statements with regard to hormonal disorders.

Grave's disease is an autoimmune disorder results due to hypothyroidism.

Elevated level of cortisol in the blood results in Cushing's syndrome.

The deficiency of thyroxine in children leads to physical and mental retardation and result cretinism.

Hyposecretion of aldosterone and cortisol results Addison's disease.

None

16.

Statement (SI) : In Elephantiasis, genital organs are also often affected, resulting in gross deformities. Statement (SII) : Filarial worms live for many years, in the lymphatic vessels of. the lower limbs.

Statement SI is incorrect but SII is correct

Statements SI and SII are incorrect

Statement SI is correct but SII is incorrect

Statements SI and SII are correct

None

17.

Which cell organelle plays an important role in detroxification of many poisons and drugs in a cell ?

mitochondria

smooth endoplasmic reticulum

Iysosomes

vacuoles

None

18.

Third stage larva of Wuchereria bancrofti carried by Culex mosquito is called

Merozoite

Microfilariae

Cysticercus

Trophozoite

None

19.

The inflammatory response is triggered whenever body tissues are injured. E.g. it occurs in response to physical trauma (a blow), intense heat and irritating chemicals as well as infection by viruses, fungi and bacteria.

Arrange the major events involved in the inflammatory process in the correct order as they occur in the body.

i. Mast cells secrete histamine and cytokines.

ii. Phagocytosis by monocytes.

iii. Cytokines attract neutrophils and monocytes to injured site.

iv. Tissue injury

v. Diapedesis or emigration of neutrophils & monocytes into the area through the capillary.

vi. Vasodilation of arterioles & increased capillary permeability causes redness and swelling.

iv) i) v) vi) iii) ii)

iv) vi) iii) ii) i) v)

iv) i)iii) vi) v) ii)

iv) i) vi) iii) v) ii)

None

20.

AIDS is caused by HIV. Among the following, which one is not a mode of transmission of HIV?

Sharing the infected needles

Shaking hands with infected persons

Sexual contact with infected persons

Transfusion of contaminated blood

None

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